CAPACITABINE



Xeloda


Indication:

It is used alone or with other treatments/medications to treat certain types of cancer (e.g., of the breast, colon, rectum). It works by slowing or stopping cancer cell growth and by decreasing tumor size.



Brand name: Xeloda

Active Ingeridents: Capecitabine

Company Name: Roche Pharmaceuticals

Package: 10 tabs in a strip

Strength : 500mg

Mechanism of action:


Xeloda (Capecitabine) Is A Prodrug That Is Converted To Fluorouracil Following Oral Administration, Which In Turn Inhibits Thymidylate Synthetase, Blocking The Methylation Of Deoxyuridylic Acid To Thymidylic Acid, Interfering With DNA, And To A Lesser Degree, RNA Synthesis.


Dosage and Administration:


  • Taken as a pill by mouth.

  • Take after food (within 30 minutes of a meal) with water. (Usually taken in a divided dose 12 hours apart).

  • Tablets come in 2 sizes; 150mg and 500mg.

  • Do not crush, chew or dissolve tablets.

  • The amount of Xeloda (Capecitabine) that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

Side effects:


Diarrhoea, Nausea And Vomiting, Stomatitis, Palmar-Plantar Syndrome, Dermatitis. Fatigue, Mucosal Inflammation, Pyrexia, Asthenia And Lethargy; Headache, Dizziness And Insomnia; Lower Limb Oedema, Anorexia, Dehydration. Potentially Fatal: Cardiotoxicity, Bone-Marrow Depression And Hyperbilirubinaemia.


Store:


Xeloda (Capecitabine) room temperature away from moisture and heat.














Precaution:



  • Before starting Xeloda (Capecitabine) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.

  • Avoid use of antacids within 2 hours of taking Xeloda (Capecitabine).

  • If you are on warfarin (Coumadin速) as a blood-thinner, adjustments may need to be made to your dose based on blood work.

  • Xeloda (Capecitabine) may be inadvisable if you have had a hypersensitivity (allergic) reaction to fluorouracil.

  • Do not receive any kind of immunization or vaccination without your doctor's approval while taking Xeloda (Capecitabine).

  • Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (Xeloda (Capecitabine) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

WARNING:


Xeloda is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.



Capegard



Indication:

It is used alone or with other treatments/medications to treat certain types of cancer (e.g., of the breast, colon, rectum). It works by slowing or stopping cancer cell growth and by decreasing tumor size.



Brand name: Capegard

Active Ingeridents: Capecitabine

Company Name: Cipla

Package: 10 tabs in a strip

Strength :500mg

Mechanism of action:


Capegard (Capecitabine) Is A Prodrug That Is Converted To Fluorouracil Following Oral Administration, Which In Turn Inhibits Thymidylate Synthetase, Blocking The Methylation Of Deoxyuridylic Acid To Thymidylic Acid, Interfering With DNA, And To A Lesser Degree, RNA Synthesis.


Dosage and Administration:


  • Taken as a pill by mouth.

  • Take after food (within 30 minutes of a meal) with water. (Usually taken in a divided dose 12 hours apart).

  • Tablets come in 2 sizes; 150mg and 500mg.

  • Do not crush, chew or dissolve tablets.

  • The amount of Capegard (Capecitabine) that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

Side effects:


Diarrhoea, Nausea And Vomiting, Stomatitis, Palmar-Plantar Syndrome, Dermatitis. Fatigue, Mucosal Inflammation, Pyrexia, Asthenia And Lethargy; Headache, Dizziness And Insomnia; Lower Limb Oedema, Anorexia, Dehydration. Potentially Fatal: Cardiotoxicity, Bone-Marrow Depression And Hyperbilirubinaemia.


Store:


Capegard (Capecitabine) room temperature away from moisture and heat.


Precaution:


  • Before starting Capegard (Capecitabine) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.

  • Avoid use of antacids within 2 hours of taking Capegard (Capecitabine)

  • If you are on warfarin (Coumadin速) as a blood-thinner, adjustments may need to be made to your dose based on blood work.

  • Capegard (Capecitabine) may be inadvisable if you have had a hypersensitivity (allergic) reaction to fluorouracil.

  • Do not receive any kind of immunization or vaccination without your doctor's approval while taking Capegard (Capecitabine).

  • Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D Capegard (Capecitabine) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

WARNING:


Capegard is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.


Capnat



Indication:

It is used alone or with other treatments/medications to treat certain types of cancer (e.g., of the breast, colon, rectum). It works by slowing or stopping cancer cell growth and by decreasing tumor size.



Brand name: Capnat

Active Ingeridents: Capecitabine

Company Name: Natco Pharma

Package: 10 tabs in a strip

Strength : 500mg

Mechanism of action:


Capnat (Capecitabine) Is A Prodrug That Is Converted To Fluorouracil Following Oral Administration, Which In Turn Inhibits Thymidylate Synthetase, Blocking The Methylation Of Deoxyuridylic Acid To Thymidylic Acid, Interfering With DNA, And To A Lesser Degree, RNA Synthesis.


Dosage and Administration:


  • Taken as a pill by mouth.

  • Take after food (within 30 minutes of a meal) with water. (Usually taken in a divided dose 12 hours apart).

  • Tablets come in 2 sizes; 150mg and 500mg.

  • Do not crush, chew or dissolve tablets.

  • The amount of Capnat (Capecitabine) that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

Side effects:


Diarrhoea, Nausea And Vomiting, Stomatitis, Palmar-Plantar Syndrome, Dermatitis. Fatigue, Mucosal Inflammation, Pyrexia, Asthenia And Lethargy; Headache, Dizziness And Insomnia; Lower Limb Oedema, Anorexia, Dehydration. Potentially Fatal: Cardiotoxicity, Bone-Marrow Depression And Hyperbilirubinaemia.


Store:


Capnat (Capecitabine) room temperature away from moisture and heat.













Precaution:


  • Before starting Capnat (Capecitabine) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.

  • Avoid use of antacids within 2 hours of taking Capnat (Capecitabine).

  • If you are on warfarin (Coumadin速) as a blood-thinner, adjustments may need to be made to your dose based on blood work.

  • Capnat (Capecitabine) may be inadvisable if you have had a hypersensitivity (allergic) reaction to fluorouracil.

  • Do not receive any kind of immunization or vaccination without your doctor's approval while takingCapnat (Capecitabine).

  • Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D Capnat (Capecitabine) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

WARNING:


Capnat is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.