DECITABINE



Decitabine


Indication:


This medicine is Treating myelodysplastic syndromes (MDS) (eg, certain types of anemia or leukemia). Decitabine is a nucleoside analog. It works by blocking cell growth.



Brand name:Decitabine

Active Ingeridents:Decitabine

Company Name:Sandoz

Package: Vial

Strength :50 mg

Mechanism of action:


Decitabine is a hypomethylating agent. It hypomethylates DNA by inhibiting DNA methyltransferase.

It functions in a similar manner to azacitidine, although decitabine can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains.


Dosage and Administration:


  • As an infusion into the vein (intravenous or IV).

  • The actual dosage of Decitabine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact dosage and schedule.

Side effects:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; cough; diarrhea; dizziness; hair loss; headache; joint or muscle pain; loss of appetite; nausea; stomach pain or upset; trouble sleeping; vomiting.


Store:


Decitabine is usually handled and stored by a health care provider. If you are using decitabine at home, store decitabine as directed by your pharmacist or health care provider. Keep decitabine out of the reach of children and away from pets.


Precaution:


  • Before starting Decitabine treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.

  • Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Decitabine.

WARNING:


Decitabine is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.




Natdecita



Indication:


Tasigna (Nilotinib) is used to treat a certain type of blood cancer (chronic myelogenous leukemia-CML). It works by slowing or stopping the growth of cancer cells.



Brand name: Natdecita

Active Ingeridents:Decitabine

Company Name:Natco

Package:Vial

Strength :50 mg

Mechanism of action:


Natdecita (Decitabine) is a hypomethylating agent. It hypomethylates DNA by inhibiting DNA methyltransferase.

It functions in a similar manner to azacitidine, although Natdecita (Decitabine)can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains.


Dosage and Administration:


  • As an infusion into the vein (intravenous or IV).

  • The actual dosage of Natdecita (Decitabine)that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact dosage and schedule.

Store:


Natdecita (Decitabine)is usually handled and stored by a health care provider. If you are using Natdecita (Decitabine)at home, store Natdecita (Decitabine)as directed by your pharmacist or health care provider. Keep Natdecita (Decitabine)out of the reach of children and away from pets.


Side effects:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; cough; diarrhea; dizziness; hair loss; headache; joint or muscle pain; loss of appetite; nausea; stomach pain or upset; trouble sleeping; vomiting.


Precaution:


  • Before starting Natdecita (Decitabine)treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.
  • Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Decitabine.

WARNING:


Natdecita is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.