TENOFOVIR-EMTRICITABINE



Tavin-EM


Indication:


Tavin-EM (Tenofovir/Emtricitabine) are antiviral drugs that work by preventing HIV (human immunodeficiency virus) cells from multiplying in the body.

Tavin-EM (Tenofovir/Emtricitabine) is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, but it can be used to treat HIV in adults and children who are at least 12 years old and weigh at least 17 kilograms (37 pounds).



Brand name:Tavin-EM

Active Ingeridents:Tenofovir/Emtricitabine

Company Name:Emcure

Package:30 Tablets

Strength :Tenofovir 300mg +Emtricitabine 200mg

Mechanism of action:


Tenofovir:

Tenofovir inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. Specifically, the drugs are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain. However, unlike the natural deoxynucleotides substrates, NRTIs and NTRTIs (nucleoside/tide reverse transcriptase inhibitors) lack a 3'-hydroxyl group on the deoxyribose moiety. As a result, following incorporation of an NRTI or an NtRTI, the next incoming deoxynucleotide cannot form the next 5'-3' phosphodiester bond needed to extend the DNA chain. Thus, when an NRTI or NtRTI is incorporated, viral DNA synthesis is halted, a process known as chain termination. All NRTIs and NtRTIs are classified as competitive substrate inhibitors.

Emtricitabine:

Emtricitabine works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. Emtricitabine is a synthetic nucleoside analogue of cytidine. It is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which is responsible for the inhibition of HIV-1 reverse transcriptase. It competes with the natural substrate deoxycytidine 5'-triphosphate and incorporates into nascent viral DNA, resulting in early chain termination. Therefore emtricitabine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate deoxycytidine 5'-triphosphate and by its incorporation into viral DNA. By inhibiting HIV-1 reverse transcriptase, emtricitabine can help to lower the amount of HIV, or "viral load", in a patient's body and can indirectly.


Dosage and Administration:


Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

  • You may take this medicine with or without food.

  • Use Tavin-EM (Tenofovir/Emtricitabine) regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

  • While using this medicine, you may need frequent blood tests. Your kidney and liver function, or bone mineral density may also need to be checked.

Side effects:


Nausea, vomiting, diarrhea, headache, dizziness, trouble sleeping, back pain, or change in the color of skin on your palms or soles of your feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


Store:


Tavin-EM (Tenofovir/Emtricitabine) room temperature away from moisture and heat or cold. Do not freeze.








Precaution:


Before taking Tavin-EM (Tenofovir/Emtricitabine), tell your doctor or pharmacist if you are allergic to either of the medications; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, liver problems (hepatitis B, hepatitis C, cirrhosis), alcohol use, bone problems (such as bone disease, bone loss/osteoporosis, weak/broken bones), kidney disease.


WARNING:


Tavin-EM (Tenofovir/Emtricitabine) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.



Tenvir -EM



Indication:


Tenvir -EM (Tenofovir/Emtricitabine) are antiviral drugs that work by preventing HIV (human immunodeficiency virus) cells from multiplying in the body.

Tavin-EM (Tenofovir/Emtricitabine) is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, but it can be used to treat HIV in adults and children who are at least 12 years old and weigh at least 17 kilograms (37 pounds).



Brand name:Tenvir -EM

Active Ingeridents:Tenofovir/Emtricitabine

Company Name:Cipla

Package:30 Tablets

Strength :Tenofovir 300mg +Emtricitabine 200mg

Mechanism of action:


Tenofovir:

Tenofovir inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. Specifically, the drugs are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain. However, unlike the natural deoxynucleotides substrates, NRTIs and NTRTIs (nucleoside/tide reverse transcriptase inhibitors) lack a 3'-hydroxyl group on the deoxyribose moiety. As a result, following incorporation of an NRTI or an NtRTI, the next incoming deoxynucleotide cannot form the next 5'-3' phosphodiester bond needed to extend the DNA chain. Thus, when an NRTI or NtRTI is incorporated, viral DNA synthesis is halted, a process known as chain termination. All NRTIs and NtRTIs are classified as competitive substrate inhibitors.

Emtricitabine:

Emtricitabine works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. Emtricitabine is a synthetic nucleoside analogue of cytidine. It is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which is responsible for the inhibition of HIV-1 reverse transcriptase. It competes with the natural substrate deoxycytidine 5'-triphosphate and incorporates into nascent viral DNA, resulting in early chain termination. Therefore emtricitabine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate deoxycytidine 5'-triphosphate and by its incorporation into viral DNA. By inhibiting HIV-1 reverse transcriptase, emtricitabine can help to lower the amount of HIV, or "viral load", in a patient's body and can indirectly.


Dosage and Administration:


Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

  • You may take this medicine with or without food.

  • Use Tenvir-EM (Tenofovir/Emtricitabine) regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

  • While using this medicine, you may need frequent blood tests. Your kidney and liver function, or bone mineral density may also need to be checked.

Store:


Tenvir-EM (Tenofovir/Emtricitabine) room temperature away from moisture and heat or cold. Do not freeze.


Side effects:


Nausea, vomiting, diarrhea, headache, dizziness, trouble sleeping, back pain, or change in the color of skin on your palms or soles of your feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


Precaution:


Before taking Tenvir-EM (Tenofovir/Emtricitabine), tell your doctor or pharmacist if you are allergic to either of the medications; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, liver problems (hepatitis B, hepatitis C, cirrhosis), alcohol use, bone problems (such as bone disease, bone loss/osteoporosis, weak/broken bones), kidney disease.


WARNING:


Tenvir-EM (Tenofovir/Emtricitabine) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.






















Truvada



Indication:


Truvada (Tenofovir/Emtricitabine) are antiviral drugs that work by preventing HIV (human immunodeficiency virus) cells from multiplying in the body.

Truvada (Tenofovir/Emtricitabine) is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, but it can be used to treat HIV in adults and children who are at least 12 years old and weigh at least 17 kilograms (37 pounds).



Brand name:Truvada

Active Ingeridents:Tenofovir/Emtricitabine

Company Name:Gilead

Package:30 Tablets

Strength :Tenofovir 300mg +Emtricitabine 200mg

Mechanism of action:


Tenofovir inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. Specifically, the drugs are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain. However, unlike the natural deoxynucleotides substrates, NRTIs and NTRTIs (nucleoside/tide reverse transcriptase inhibitors) lack a 3'-hydroxyl group on the deoxyribose moiety. As a result, following incorporation of an NRTI or an NtRTI, the next incoming deoxynucleotide cannot form the next 5'-3' phosphodiester bond needed to extend the DNA chain. Thus, when an NRTI or NtRTI is incorporated, viral DNA synthesis is halted, a process known as chain termination. All NRTIs and NtRTIs are classified as competitive substrate inhibitors.

Emtricitabine:

Emtricitabine works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. Emtricitabine is a synthetic nucleoside analogue of cytidine. It is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which is responsible for the inhibition of HIV-1 reverse transcriptase. It competes with the natural substrate deoxycytidine 5'-triphosphate and incorporates into nascent viral DNA, resulting in early chain termination. Therefore emtricitabine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate deoxycytidine 5'-triphosphate and by its incorporation into viral DNA. By inhibiting HIV-1 reverse transcriptase, emtricitabine can help to lower the amount of HIV, or "viral load", in a patient's body and can indirectly.


Dosage and Administration:


Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

  • You may take this medicine with or without food.

  • Use Truvada (Tenofovir/Emtricitabine) regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

  • While using this medicine, you may need frequent blood tests. Your kidney and liver function, or bone mineral density may also need to be checked.

Store:


Truvada(Tenofovir/Emtricitabine) room temperature away from moisture and heat or cold. Do not freeze.


Side effects:


Nausea, vomiting, diarrhea, headache, dizziness, trouble sleeping, back pain, or change in the color of skin on your palms or soles of your feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


Precaution:


Before taking Truvada (Tenofovir/Emtricitabine), tell your doctor or pharmacist if you are allergic to either of the medications; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, liver problems (hepatitis B, hepatitis C, cirrhosis), alcohol use, bone problems (such as bone disease, bone loss/osteoporosis, weak/broken bones), kidney disease.


WARNING:


Truvada (Tenofovir/Emtricitabine) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.