VINORELBINE TARTRATE



Navelbine


Indication:


It is used in the treatment of Non-small cell lung cancer, Some healthcare providers may also give this drug for breast cancer, ovarian cancer, or Hodgkin's disease.



Brand name:Navelbine

Active Ingeridents:Vinorelbine

Company Name:PIEERE Fabre Pharma

Package: Vial

Strength :50mg /5ml

Mechanism of action:


The antitumor activity of Navelbine (Vinorelbine) is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Navelbine (Vinorelbine) binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Like other vinca alkaloids, Navelbine (Vinorelbine) may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.


Dosage and Administration:


  • Navelbine (Vinorelbine) is given through a vein by intravenous injection (IV push) or infusion (IV). Navelbine (Vinorelbine) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. The nurse or doctor who gives this drug must be carefully trained. If you notice pain, redness or swelling at the IV site while you are receiving Navelbine (Vinorelbine) tartrate, alert your health care professional immediately.
  • The amount of Navelbine (Vinorelbine) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer being treated. Your doctor will determine your dose and schedule.

Store:


Store at room temperature away from moisture and heat.


Side effects:


Nausea, vomiting, fatigue, constipation, diarrhea, dizziness, muscle aches, joint pain, or irritation at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.


Precaution:


Before using Navelbine (Vinorelbine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia, thrombocytopenia).




Warning


Navelbine (Vinorelbine) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.



Vinrelbine Injection



Indication:


It is used in the treatment of Non-small cell lung cancer, Some healthcare providers may also give this drug for breast cancer, ovarian cancer, or Hodgkin's disease.



Brand name:Vinrelbine Injection

Active Ingeridents:Vinorelbine

Company Name: Pfizer

Package:vial

Strength :50mg /5ml

Mechanism of action:


The antitumor activity of Vinorelbine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Like other vinca alkaloids, Vinorelbine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.


Dosage and Administration:


  • Vinorelbine is given through a vein by intravenous injection (IV push) or infusion (IV). Vinorelbine is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. The nurse or doctor who gives this drug must be carefully trained. If you notice pain, redness or swelling at the IV site while you are receiving Vinorelbine tartrate, alert your health care professional immediately.
  • The amount of Vinorelbine you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer being treated. Your doctor will determine your dose and schedule.

Store:


Store at room temperature away from moisture and heat.


Side effects:


Nausea, vomiting, fatigue, constipation, diarrhea, dizziness, muscle aches, joint pain, or irritation at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.


Precaution:


Before using Vinorelbine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia, thrombocytopenia).



WARNING:


Vinrelbine Injection is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.




Vinotec



Indication:


It is used in the treatment of Non-small cell lung cancer, Some healthcare providers may also give this drug for breast cancer, ovarian cancer, or Hodgkin's disease.



Brand name:Vinotec

Active Ingeridents: Vinorelbine

Company Name:United Biotech

Package:Vial

Strength :50mg /10mg

Mechanism of action:


The antitumor activity of Vinotec (Vinorelbine) is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinotec (Vinorelbine) binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Like other vinca alkaloids, Vinotec (Vinorelbine) may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.


Dosage and Administration:


  • Vinotec (Vinorelbine) is given through a vein by intravenous injection (IV push) or infusion (IV). Vinotec (Vinorelbine) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. The nurse or doctor who gives this drug must be carefully trained. If you notice pain, redness or swelling at the IV site while you are receiving Vinotec (Vinorelbine) tartrate, alert your health care professional immediately.
  • The amount of Vinotec (Vinorelbine) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer being treated. Your doctor will determine your dose and schedule.

Store:


Store at room temperature away from moisture and heat.


Side effects:


Nausea, vomiting, fatigue, constipation, diarrhea, dizziness, muscle aches, joint pain, or irritation at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.


Precaution:


Before using Vinotec (Vinorelbine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia, thrombocytopenia).

WARNING:


Vinotec (Vinorelbine) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.