Apnat 60 Tablet

Description of Apnat 60 (Apalutamide 60mg) tablet

Each tablet of Apnat 60 consists of Apalutamide 60mg, which is a cancer product that is used to treat prostate carcinoma among male patients. The drug is an androgen receptor antagonist that suppresses the growth of the endogenous on cancer cells.

Indications of Apnat 60 (Apalutamide 60mg) tablet

Men who have metastatic castration-resistant prostate cancer are most often recommended the Apnat 60 (Apalutamide 60mg) tablet. It can also be given to certain people with non-metastatic castration-resistant prostate cancer if their circumstances are kind of appropriate.

Mechanism of action of Apnat 60 (Apalutamide 60mg) tablet

Apalutamide assists by stopping signals from the androgen receptors, which reduces ability of androgens to assist growth of prostate cancer cells. This interruption leads to less spreading of cancer cells and more of cells dying.

How to consume Apnat 60 (Apalutamide 60mg) tablet

People must use Apalutamide tablet strictly in amount the doctor decides for you. Most often, drug is taken one time every day, and you can take it with food or without having any food. You have to make sure about swallowing each tablet whole and should not break, chew or open it.

Side Effects of Apnat 60 (Apalutamide 60mg) tablet

1. Common side effects

• Feeling tired
• Experiencing hot flashes
• Problems with diarrhea
• Joint hurting
• Appetite gets lower

2. Serious side effects

• Having a seizures sometimes
• Indications of liver trouble (like having yellow skin or eyes)
• Allergic issues (rashes itchy, or swelling)

3. Rare side effects

• Heart-related cases (myocardial infarct for example)
• Bones can break
• Mood or action changes

Safety Advice for Apnat 60 (Apalutamide 60mg) tablet

People who are using Apalutamide need proper checking for probable bad impacts, for example, nerve symptoms including seizure. The doctor might ask for often checking of the liver working too.

Breastfeeding: The use of this medicine is considered unsafe because this medicine passes through breast milk, so it is better to avoid during breastfeeding.

Pregnancy: The use of this medicine is considered unsafe because this medicine may cause harmful effect on the fetus. Kindly consult with your doctor for further information.

Alcohol: There must be a reduction in taking alcohol since it might give higher risk of some impacts.

Liver: Patients having liver problems should use with care.

Lungs: If some lung disease is already there, it must be talked with your doctor before you start.

Kidney: Patients having kidney problems should use with care.

Driving: Tiredness and feeling dizzy can be possible, so machines and driving must be done with care.

Interaction of Apnat 60 (Apalutamide 60mg) tablet

• Drug-Drug Interaction :

Cabotegravir x Apalutamide

It is contraindicated to use this medicine because the use of Apalutamide will decrease the effect of cabotegravir by increasing its metabolism.

Amiodarone x Apalutamide

Use alternative drug because the use of apalutamide will decrease the effect of amiodarone by affecting its hepatic enzyme metabolism.

Acetaminophen x Apalutamide

Therapy should be administered with caution because the use of apalutamide will decrease the effect of acetaminophen by increasing its metabolism.

Siponimod x Apalutamide

Therapy should be administered with caution because the combination of this medicine increase the risk of infection.

Taurine x Apalutamide

Apalutamide use counters the effect of taurine in an unidentified interaction mechanism.

• Drug-Food Interaction:

High cholesterol:

People who have been reported to have a history of hypercholesterolemia should not be exposed to this drug as the agent has been found to also be linked with a high risk of being subjected to ischemic cardiovascular events.

Alcohol:         

Alcoholic beverage use during treatment can cause confusion, somnolence and vertigo, thus increasing the chances of accidents.

• Drug-Disease Interaction:

Liver Impairment:

Prescription of this therapeutic regimen should be done cautiously because the hepatic metabolism can be compromised in patients with moderate to severe liver dysfunction therefore affecting the effectiveness of the drug..

Osteoporosis:

The treatment pattern should be used prudently, since the exposure to this agent could enhance the risk of falls and fractures.

Seizures:

The therapeutic agent used be used with caution in individuals with seizures history,, traumatic brain injury, cerebrovascular accident, brain neoplasm or infection since the agent can trigger seizures , the use of the agent should be discontinued when the seizures recur during  treatment.

Contraindication of Apnat 60 (Apalutamide 60mg) tablet

It is contraindicated to use this medicine in patient who have a history of allergy.

Do not take this medicine if you are pregnant.

Cerebrovascular, cardiovascular events, falls, fractures, and seizures were reported.

Dosage of Apnat 60 (Apalutamide 60mg) tablet

The doctor may make changes depending upon personal tolerance and how the treatment is working.

Storage of Apnat 60 (Apalutamide 60mg) tablets 

The storage of Apalutamide tablets must be carried out at average temperature of the room without being subjected to excessive moisture or heat. You should always have them inside packet they are in and out of reach of children.

Missed Dose to Apnat 60 (Apalutamide 60mg) tablets

If you miss one tablet, just use planned next dose on the regular schedule. Taking two tablets together to replace a missed one is not required. Do not try to increase your next dose for this.

Other General Information of Apnat 60 (Apalutamide 60mg) tablets 

The use of Apnat 60 Tablet might create dry skin, so using proper moisturizer is recommended by the doctors. Stay hydrated by drinking water and eat with more balanced as much as you can. Attending frequent checkups with doctor is important during treatment; you should notify any strange side effects as soon as possible. In case you need further advice or more information about your case, then visit your physician.

FAQs about Apnat 60 (Apalutamide 60mg) tablet

1. May Apnat 60 tablet cause infertility?

Currently there is scanty evidence that demonstrates the effect, preclinical studies indicate a possibility of an effect on reproductive paramaters.

2. Can Apalutamide be used together with other pharmacologic agents?

Patients are expected to inform the physician treating them of all the co-existing medications, to alleviate the likelihood of drug-drug interaction.

3. What is necessary if an overdose happened?

Consultation with a doctor should be immediately sought in cause of an overdose.

4. Does the Apnat 60 tablet belong to the group of chemotherapeutic agents?

This drug is not a cytotoxic chemotherapy agent- it is an anti-androgen agent.

5. In case of perceived improvement should the treatment be stopped?

It is not recommended to suddenly stop using the medication before the prescribed dose of the therapy is achieved because early withdrawal can promote the growth of the remaining neoplastic cells.

Fact Box of Apnat 60 (Apalutamide 60mg) tablet:

Field	Details
Generic/Molecule Name	Apalutamide
Therapeutic Class	Anti-androgen
Pharmacological Class	Androgen receptor blocker
Dosage form	Tablet
Habit forming	No
Indication	Prostate cancer

References

• Apalutamide [Summary of Product Characteristics]. Latina, Italy: Janssen Cilag SpA; 2019. [Accessed 27 Jul. 2023]. (online) Available from: https://www.ema.europa.eu/en/documents/product-information/erleada-epar-product-information_en.pdf
• National Cancer Institute. Apalutamide. [Accessed 27 Jul. 2023]. (online) Available from: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/apalutamide
• Prescribing Information. Horsham, USA: Janssen Products, LP; 2024. [Accessed 30 Oct. 2025] (online) Available from: https://www.jnjlabels.com/package-insert/product-monograph/prescribing-information/ERLEADA-pi.pdf