Trade name : Anabrez
Active ingredient : Anastrazole
Strength availability : 1MG
Manufactured by : Sun Pharmaceuticals Ltd
Package : 28 tablets in a carton


Anabrez tablets belongs to classification of anticancer drugs and it contains active constituents like Anastrazole. Anastrazole is identify as non-steroidal Aromatase inhibitor. And which available in the form of tablet. Anabrez is able to reduce the estrogen production by preventing Aromatase, an enzyme essential for changes of androgen into estrogen. Anastrazole which involves in hormonal treatment. It is prescription drugs which is used under the guidance of pharmacist, the main ingredient which is used as anastrozole.


Anabrez tablets are used in patients for supporting treatment of postmenopausal women with hormone receptor positive breast cancer. Anabrez is used for treatment of patients require for first line therapy in post menopausal women having receptor positive or hormone receptor exotic locally progressive or metastatic breast carcinoma Anabrez tablets used for treatment of patients require for second line therapy in patients having metastatic breast cancer, in post menopausal women with cancer advancement consequently tamoxifen treatment. Treatment intermittently perform to Anabrez tablets in Patients with hormone receptor negative disorder, or patient who are not respond to tamoxifen .


In adult for the treatment of breast cancer: Anabrez 1mg recommended dose is one tablet of 1mg, taken once a day, Administrated orally with or without food Patients having postmenopausal women with hormone receptor +ve in adjuvant treatment in early invasive breast cancer. Duration of treatment is 5 years. In pediatric patients for the treatment of breast cancer: Anabrez tablet is not used and no inadequate data on safety and efficacy. Anabrez should be followed for five years in ATAC trials In renal impairment patients or for elderly patients no dose adjustments acquired In mild to moderate hepatic impairment condition no dose adjustment takes place.


Anastrazole concurrently prohibits an enzyme Aromatase which helped for converting of ambient estrogen to estrone via adrenally growth androstenedione by Aromatase in peripheral tissues Hence the drug prevent Aromatase may cause decrease in plasma and tumor accumulation of estrogen, following to reducing of tumor lump or slow the development of tumor growth


The drug absorbs rapidly and obtain maximum serum concentration occurs within 2 hours. Effects of food: Reduces food rate but not all the extent of Anastrazole absorption.
The drug Anastrazole has human serum protein bound is 40%
The Anastrazole metabolism is occurred via N-Dealkylation, hydroxylation and Glucuronidation The metabolites of Anastrazole are; Triazole-major circulating metabolite which has poor pharmacological activity A glucoronide conjugate of hydroxyl Anastrazole A glucoronide conjugate of Anastrazole
Nearly 85% of Anastrazole reclaimed in feces and urine in Hepatic metabolism: 10% total clearance in Renal metabolism The Anastrazole half life is 50 hours


Anabrez tablet will change the effect of other drugs, it concluded as CYP-450 prohibition. While tamoxifen combination with Anastrazole will reduce the plasma concentration of Anastrazole by 27%. Avoid continuse use with Anabrez tablet which may cause depletion of its pharmacological activity in Estrogen therapy. Concomitant use of Warfarin with Anastrazole, it did not alter the anti-coagulant effect.


The dose missed by patient should have the dose immediately before the next dose timing reaches , or leave the missed dose and continue the regular schedule. Remember do not have double dose at a time Please consult with doctor for further details.


The patient administrating with tamoxifen may have increase in serum cholesterol level correlated by Anabrez tablets Condition of ischemic cardiovascular action: There is a chance of raising of proportion of ischemic cardiovascular effects while getting Anabrez tablets. When patients getting Anabrez tablet have chance of getting Cholesterol due to lowering total hip bone density and lumbar spine density


The drug excreted into breast milk taking account on this, discussion should done on whether to discontinue the breast feeding or the drug. Use of drug is contraindicated during breastfeeding. It is unclear the effect of new born babies.


Common side effects :
Neoplasm, Pain , back pain, headache, abdominal pain, infection, injury, , chest pain, Asthenia, , cyst, flu like syndrome Cardiovascular: Vasodilatation, hypertension Digestive: Nausea, constipation, diarrhea, dyspepsia, GI disorders Blood related effects: Lymph edema, anemia Metabolism: Peripheral edema, weight gain, hypercholesterolemia Musculoskeletal: Arthritis, arthralgia, osteoporosis, fracture, bone pain, arthrosis, joint pain, Myalgia Nervous: Depression, insomnia, dizziness, anxiety, paresthesia Respiratory: Pharyngitis, cough increased, dyspnea, sinusitis, bronchitis Skin: Rashes, sweating Eye: Cataract specified Urogenital:, urinary tract infection, breast pain, breast neoplasm, vulvovaginitis, vaginal hemorrhage, vaginitis ; Leucorrhea

We'd Like to Hear From You!


1., a fully licensed and regulated pharmacy, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.
2. will not dispense any prescription medication without a valid prescription from a licensed physician.
3. If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.
4. The drug information provided in the is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.
5. requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from
6. At, a Caregiver can order prescription medicines on your behalf.

This information should not be used to decide whether to accept this product or any other medicine. Only a health care provider is knowledge and training to decide that a medicine suitable for a specific patient. This information does not support any drug as safe, are effective or approved for the treatment of any patient or health condition. It's simple a brief overview of general information about this product. It does not include all information on possible applications, indications, warnings, precautions, interactions, adverse effects or risks that may be relevant to this product. This information is not specific medical advice and does not replace information obtained from your health care provider. You should check with your health care provider for complete information about the risks and benefits of using this product.