Ipoget 1gm (Ifosfamide)

Ifosfamide
Contact us for more information
Цвет:
Вариант:
Wishlist Compare
Brand nameIpogetInternational trade nameIfexActive substanceIfosfamideStrength1gmCategoryAnti Cancer

Description of Ipoget 1gm (Ifosfamide 1gm)

Ifosfamide is generic form of brand name Ipoget 1gm (Ifosfamide 1gm)Ipoget 1gm (Ifosfamide 1gm) is an antineoplastic agent chemically associated to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent. Ipoget 1gm (Ifosfamide 1gm) is a prescription medicine which is used under the supervision of medical oncologist

Medical use /Indication of Ipoget 1gm (Ifosfamide 1gm)

  • Ipoget 1gm (Ifosfamide 1gm)is used for the treatment in patientswith relapsed testicular cancer and germ cell tumors
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Sarcomas (soft-tissue, osteogenic sarcoma, Ewing's sarcoma)
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Non-Hodgkin's lymphoma
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Hodgkin's disease
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Non-small cell and small cell lung cancer
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Bladder cancer
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Head and neck cancer
  • Ipoget 1gm (Ifosfamide 1gm) is used for the treatment in patients with Cervix cancer

Mechanism of Action Ipoget 1gm (Ifosfamide 1gm)

The proper mechanism of Ifosfamide has not been described but occur to be like other alkylating agents. Ifosfamide mechanism by sticking the cancer cell’s DNA (the cell’s genetic code) composed so which it can't come apart again. This means which the cell will not multiply and grow.

ADME of Ipoget 1gm (Ifosfamide 1gm)

Time to high plasma of Ipoget 1gm (Ifosfamide 1gm) is 20-30 minutes and the bioavailability are 90-100%

Volume of distribution is 33L

Ipoget 1gm (Ifosfamide 1gm) is extensively metabolized and has metabolites of 3-dechloroethylifosfamide, 2- dechloroethylifosfamide and carboxyifosfamide

Ipoget 1gm (Ifosfamide 1gm) is eliminated at high dose of 5000mg/m2 in urine 70-86% and at low dose 1600-2400 about 12-16%.
Half- life for high dose of 3800-5000mg/m2 is 15hr and 7hr for low dose of 1800-2400 mg/m2

Side effects of Ipoget 1gm (Ifosfamide 1gm)

  • Alopecia
  • Malaise
  • Dysphagia
  • Low WBC count
  • Low platelet count
  • Loss of hair
  • Menopause
  • Fertility loss
  • Vomiting and nausea
  • Hypotension
  • Central neurotoxicity

Precautions of Ipoget 1gm (Ifosfamide 1gm)

  • With Ipoget 1gm (Ifosfamide 1gm)causes Haemorrhagic cystitis reported
  • Stop treatment if it occurs Confusion and coma due to CNS toxicity have been associated with therapy.
  • While treatment with Ipoget 1gm (Ifosfamide 1gm)may occur Bone marrow suppression
  • Dose-related serious myelosuppression occurred

Drug interaction of Ipoget 1gm (Ifosfamide 1gm)

When Ipoget 1gm (Ifosfamide 1gm) interaction with CYP3A4 inducers may increase the metabolism of Ifosfamide to its active alkylating metabolites When Ipoget 1gm (Ifosfamide 1gm) interaction with CYP3A4 inhibitors may decrease the metabolism of Ifosfamide to its active alkylating metabolites perhaps reducing the effectiveness of Ifosfamide treatment

Contraindication of Ipoget 1gm (Ifosfamide 1gm)

Ipoget 1gm (Ifosfamide 1gm) is contraindicated in patients with Known hypersensitivity
Ipoget 1gm (Ifosfamide 1gm) is contraindicated in patients with Urinary outflow obstruction

Pregnancy of Ipoget 1gm (Ifosfamide 1gm)

Ipoget 1gm (Ifosfamide 1gm) will have pregnancy category D

Advice the pregnant women about potential hazard to the fetus and using during pregnancy time is contraindicated

Lactation of Ipoget 1gm (Ifosfamide 1gm)

Avoid breastfeed during the treatment with Ipoget 1gm (Ifosfamide 1gm) because potential hazard to the fetus may occur.

Dosage of Ipoget 1gm (Ifosfamide 1gm)

  • Usual adult dose for testicular cancer is 1.2 g/m2, diluted to 50mg/mL IV over 30 minutes once a day with mesna administrated via IV, Oral, or continuous IV infusion given just before and 4 and 8 hours after each dose and aggressive hydration 2 to 4 L/day.
  • poget 1gm (Ifosfamide 1gm) is commonly administrated for 5days.

 

Repeated every 3 to 4 weeks :

  • The usual dosefor cervical cancer in combination with other cancer medicines as a part of the BIP regimen is 5000mg/m2 over 24 hours on day 2

Cycle repeated every 21 days :

  • The usual dose for cervical cancer in combination with other cancer medicines as a part of the BIC regimen is 2000 mg/m2IV on day 1 through 3

Cycle repeated every 21 days :

  • Paediatric dose for Malignant disease: The recommended dose is 1200 to 1800mg/m2IV for 3 to 5 days every 21 to 28 daysOr administrated has 5000mg/m2 over 24 hours infusion or 3g/m2/ day for 2 days

Storage of Ipoget 1gm (Ifosfamide 1gm)

Store the Ipoget 1gm (Ifosfamide 1gm) 2 ℃ to 8 ℃

Missed dose of Ipoget 1gm (Ifosfamide 1gm)

If the patient fails to take a dose of medicine or missed to take a dose, then should not take an extra dose, but to take the next dose at the regular time, leave the missed dose.

Brand name:
Ipoget
International trade name:
Ifex
Active substance:
Ifosfamide
Strength:
1gm
Category:
Anti Cancer
Manufacturer:
Get well Pharma
Packaging:
1 Vial
Product form:
Injection

No reviews found

Write feedback
Worldwide delivery

Our company ships from India to all countries of the world.

Genuine and Authentic products

All products supplied from the manufacturer of WHO : GMP certified facilities and ISO Certified facilitates

Economical and Affordable prices

All the products are supplying from manufacturing companies of India