Trade name : Atazor R
Active ingredient : Atazanavir & Ritonavir
Strength availability : 300mg & 100mg
Manufactured by : Emcure
Package : 30 tablets in a container
Category : Anti retroviral agents


Atazor R belongs to anti-retroviral agent which includes active ingredients like Atazanavir sulfate and Ritonavir. Both components having anti-retroviral activity and it is protease inhibitors. Protease enzyme which is Specific for cell maturation and proliferation. Atazor R is not a curable but it decrease the progression of the infection.


Atazor R tablet is a fixed dose combination which indicated for the treatment of HIV type I infected associated with AIDS. Atazor R is used only for reducing the progression of HIV virus maturation and replications It is not cure or prevents the infectious condition


Atazanavir sulfate, belongs to azapeptide HIV-1 protease inhibitor, which show activity against HIV virus type I Normally protease enzyme is specific for proteolytic cleavage of viral polyprotein into functional proteins present in infectious HIV-1. This atazanavir bounds to the active site of the protease enzyme and prohibits its activity. This inhibition causes to prevent the different of viral polyprotein; it concludes formation of immature cells and turns to non-infectious cells Ritonavir, it is a peptidomimetic HIV protease inhibitor. Low dose of Ritonavir acts as pharmacokinetic booster of concomitantly used other anti-retroviral drug Atazanavir, it increase the plasma concentration of Atazanavir concurrently


Overview :
Atazor R tablet should be taken with food The recommended dose of Atazor R based on the medical history of the patients Atazor R is a prescription medicine; it is administered under the guidance of medical practitioner The recommended dose of Atazor R for adult patients: One tablet should be taken orally with meals as a single dose.
Combination therapy :
One tablet should be taking once daily with food, if Atazor R is combined with any medicines like; Tenofovir H2 receptor antagonist: The dose of H2 receptor antagonist like famotidine should not exceed 40mg two times a day. Atazor R tablet is administered concurrently with or 10 hours after the dose of famotidine. Proton pump inhibitor: Omeprazole, a proton pump inhibitor it should not exceed to 20mg. Omeprazole should be administered in 12 hours prior to the dose of Atazor R tablet
Dose recommendation for therapy experienced patients :
If H2 receptor antagonist co administered with Atazor R tablet, dose of famotidine should not exceed to 20mg twice daily. Atazor R should be taken with food if co administered with famotidine Atazor R should not be taken, if both tenofovir and H2 receptor antagonist has been taken together. Proton pump inhibitor drugs should not taken, if treatment experienced patient taking Atazor R tablets Efavirenz should not concomitant with Atazor R tablet; it leads to decrease the Atazor R exposure


Absorption: Atazanavir is fastly absorbed , high plasma concentration is 2.5 hours. If Atazor R is taken with food, Oral bioavailability is 60-68%
Distribution: Atazanavir is highly bound to human serum protein nearly 86%. It bounds to alpha-1-acid glycoprotein and albumin (89% and 86%) respectively.
Metabolism :
The major biotransformation pathways like; Monooxygenation Dioxygenation Atazor R is highly metabolized in liver. It is metabolized by CYP3A.
Elimination :
The route of elimination is not known clearly The Atazor R in healthy persons terminal half life is 7 hours.


Some drug interaction may have chance to get; Severe skin reactions, Hyperbilirubinaemia, hepatoxicity, chronic kidney disease If patient suggested for concomitant therapy, care should be taken to reduce life threatening conditions Combination of ritonavir with some other drugs like sedative, hypnotics, anti-arrhythmia may leads to severe life threatening adverse reactions.


Atazanavir is a CYP3A4 substrate, drug which induce CYP3A4 may cause to reduce the serum concentration and therapeutic effects of the atazanavir. Concomitant use of Didanosine with Atazor R tablets leads to decrease the atazanavir exposure Interaction of Tenofovir with Atazor R: decrease the AUC and Cmin of atazanavir and increase the plasma concentration of tenofovir While Atazanavir combined with efavirenz: decrease the exposure of atazanavir Some list of medicines; Saquinavir, antacids, amiodarone, lidocaine, quinidine, carbamazepine, phenytoin, phenobarbitol etc


Patients are highly contraindicated to the components that present in the Atazor R tablet While Atazor R co administered with drugs which are highly dependent on CYP3A leads to increasing plasma concentration of interacting drugs causes life threatening conditions Atazor R concomitant with strongly CYP3A inducers may causes loss of efficacy of atazanavir List of medicines that are contraindicated; Alfuzosin, rifampicin, Irinotecan, Lurasidone, Pimozide, Midazolam, st. johns wort, lovastatin, simvastatin, sildenafil, indinavir, nevirapine.


if patient fail to administer the dose, advice them to take within a time. Or the missed dose should be swap and follow the regular drug schedule.


The serious effects that caused by Atazanavir :
Cardiac conduction abnormalities
Chronic kidney disease
Nephrolithiasis and cholelithiasis
Jaundice/scleral icterus
Diarrhea, edema
Hepatic function abnormalities
QTc prolongation.

We'd Like to Hear From You!


1., a fully licensed and regulated pharmacy, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.
2. will not dispense any prescription medication without a valid prescription from a licensed physician.
3. If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.
4. The drug information provided in the is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.
5. requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from
6. At, a Caregiver can order prescription medicines on your behalf.

This information should not be used to decide whether to accept this product or any other medicine. Only a health care provider is knowledge and training to decide that a medicine suitable for a specific patient. This information does not support any drug as safe, are effective or approved for the treatment of any patient or health condition. It's simple a brief overview of general information about this product. It does not include all information on possible applications, indications, warnings, precautions, interactions, adverse effects or risks that may be relevant to this product. This information is not specific medical advice and does not replace information obtained from your health care provider. You should check with your health care provider for complete information about the risks and benefits of using this product.