Naivex 50mg (Dolutegravir)

Dolutegravir
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Hetero Drugs Ltd

Naivex 50mg (Dolutegravir)

ManufacturerHetero Drugs LtdBrand nameNaivexInternational trade nameTivicayActive substanceDolutegravir Strength50mgCategoryHIV

Description of Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg) is additionally against retro viral medication, including Dolutegravir as a functioning part. Naivex 50mg (Dolutegravir 50mg) ought not to be utilized alone; it might consolidate with other hostile to retroviral operators for better action against HIV-1 diseases. Naivex 50mg (Dolutegravir 50mg) aren’t curing the HIV-1 disease, however used to control the quantity of HIV tallies in the body, and preclude HIV serious sick known as AIDS.

Medical use /Indication of Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg) and are broadly demonstrated for the treatment of HIV-1 disease, in grown-ups and pediatric patients with body weight of 35kg incompletely. Naivex 50mg (Dolutegravir 50mg) are advantageous while mix; not in partitioned utilize

Mechanism of Action Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg) contains contradicting to viral property against HIV make I sullying. Naivex 50mg (Dolutegravir 50mg) is stated as an Integrase inhibitor, which can counterpart to decrease HIV cell change by interceding with Integrase accomplish to the aggressive site and blockade of strands trade step happened. The viral DNA mix into have cells get stopped This trade procedure is accountable for HIV cell increment cycle. This prompts impediment of viral development

Pharmacokinetic of Naivex 50mg (Dolutegravir 50mg) 

Absorption of Naivex 50mg (Dolutegravir 50mg)

Greatest plasma concentration time of Dolutegravir is 2 to 3 hours .The persistent state level reaches inside 5 days

Distribution of Naivex 50mg (Dolutegravir 50mg)

Dolutegravir is largely bound to human plasma protein at 98.9%

Metabolism of Naivex 50mg (Dolutegravir 50mg)

The metabolism of Dolutegravir is happens through UGT1A1 with some extra commitment from CYP3A.

Elimination of Naivex 50mg (Dolutegravir 50mg)

The terminal half existence of Dolutegravir is 14 hours. The significant course of disposal is urine and as an unaltered frame through feces.

Side effects of Naivex 50mg (Dolutegravir 50mg)

The adverse effects occur in this therapy; Liver toxicity Anaphylactic reactions Immune reconstitution syndrome

The most common side effects like; Insomnia Neutrophils elevation Increase in lipase Anxiety Depression Creatine kinase elevation

Drug interaction of Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg) joins with drugs released through OCT2 or MATE1 (dofetilide or metformin), causes elongation of plasma concentration of these medicines. Naivex 50mg (Dolutegravir 50mg) joined with etravirine causes lessen in plasma dissemination of DolutegravirNaivex 50mg (Dolutegravir 50mg) at the same time used with threatening to mycobacterials, against convulsants or herbal product like st. Johns wort causes depletion in plasma dissemination of Dolutegravir. Dolutegravir is a substrate of UGT1A3, UGT1A9, BCRP and P-gp transporters. Naivex 50mg (Dolutegravir 50mg) joined with the prescription which prohibits these synthetic compounds or transporters cause, growing the plasma concentration of DolutegravirNaivex 50mg (Dolutegravir 50mg) tablets is specialist use with non-nucleoside reverse transcriptase inhibitors; causing utilization of effect of union of Naivex 50mg (Dolutegravir 50mg). If Naivex 50mg (Dolutegravir 50mg) tablets are solidifies with protease inhibitor causes decreasing in plasma appropriation of Dolutegravir.

Pregnancy of Naivex 50mg (Dolutegravir 50mg)

The pregnancy classification of Dolutegravir is B .Using Naivex 50mg (Dolutegravir 50mg) in pregnancy condition with caution, essentially in the wake of knowing the danger parts to the hatchling of these things.In Some patients placental change happens, in such conditions stop the utilization of these products.

Lactation of Naivex 50mg (Dolutegravir 50mg)

In body weight of the pediatric patients no less than 35kg, hostile to retro viral treatment is relevant. In the body weight of under 25kg: The strength of the Naivex 50mg (Dolutegravir 50mg) ought not to be evaluated.

Pediatric of Naivex 50mg (Dolutegravir 50mg)

In body weight of the pediatric patients no less than 35kg, hostile to retro viral treatment is relevant. In the body weight of under 25kg: The strength of the Naivex 50mg (Dolutegravir 50mg) ought not to be evaluated.

Dosage of Naivex 50mg (Dolutegravir 50mg)

Patients creatinine freedom, urine protein, urine glucose ought to be observed occasionally. Naivex 50mg (Dolutegravir 50mg): Comprising of 50mg of Dolutegravir

The dosage recommendation of Naivex 50mg (Dolutegravir 50mg)

The standard endorsed dosage of both the product is one tablet ought to be directed orally as a single dosage. Naivex 50mg (Dolutegravir 50mg) ought to be taken with or without meal. Naivex 50mg (Dolutegravir 50mg) ought to have the capacity to take in adults patients and pediatric having body weight of no less than 35kg

Storage of Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg) container should be kept at 25℃, protect the container away from light, moisture & heat.

Missed dose of Naivex 50mg (Dolutegravir 50mg)

Naivex 50mg (Dolutegravir 50mg), are unfriendly to retroviral prescription, if missed measurements occurred over the traverse of treatment, must be direct with therapeutic master and take after the rule as indicated by their suggestion. On the other way, the missed dose should be avoided and take the standard schedule.

Brand name:
Naivex
International trade name:
Tivicay
Active substance:
Dolutegravir
Strength:
50mg
Category:
HIV
Manufacturer:
Hetero Healthcare Ltd
Packaging:
30 Tablet
Product form:
Tablet

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