Efavir 600 drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavirenz 600mg belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Efavirenz 600mg tablet falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.
Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.
As most NNRTIs bind within the same pocket, viral strains which are resistant to Efavir (Efavirenz) are usually also resistant to the other NNRTIs, nevirapine and delavirdine. The most common mutation observed after Efavir (Efavirenz) treatment is K103N, which is also observed with other NNRTIs.
Use Efavir (Efavirenz) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container away from heat, moisture, and light.
Dizziness, trouble sleeping, drowsiness, unusual dreams, and trouble concentrating may frequently occur. These side effects may begin 1-2 days after starting this medication and usually go away in 2-4 weeks. They are also reduced by taking Efavir (Efavirenz) on an empty stomach at bedtime. Avoid alcohol and street drugs while taking Efavir (Efavirenz). They may worsen these side effects. Tiredness, headache, nausea, vomiting, and diarrhea may also occur.
Before taking Efavirenz 600mg tablet, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Efavir is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.