Cytotam 20mg (Tamoxifen)

Tamoxifen
Contact us for more information
Цвет:
Вариант:
Wishlist Compare
Cipla Ltd

Cytotam 20mg (Tamoxifen)

ManufacturerCipla LtdBrand nameCytotamInternational trade nameSoltamoxActive substanceTamoxifenStrength20mgCategoryAnti Cancer

Description  of  Cytotam 20mg (Tamoxifen 20mg)

Cytotam 20mg (Tamoxifen 20mg) is belongs to the anticancer agents and covered by film coated tablet, the drug also a nonsteroidal antiestrogen and work as a modulator with tissue selective activities for the treatment.
Cytotam 20mg (Tamoxifen 20mg)as a stimulating agent (estrogen) in metabolism of cholesterol, bone density, and cell replication in the endometrium.
Cytotam 20mg (Tamoxifen 20mg)will help for inhibition of estrogen receptor positive cancer.

INDICATIONS of  Cytotam 20mg (Tamoxifen 20mg)

Cytotam 20mg (Tamoxifen 20mg) is used to treat of early breast cancer in women whose been already treated with surgery, radiation, and chemotherapy.
Cytotam 20mg (Tamoxifen 20mg) will help to reduce the risk of developing a more serious type of breast cancer in women who had breast cancer that will not spread outer part of the milk duct where it forms (ductal carcinoma).

MECHANISM OF ACTION  of  Cytotam 20mg (Tamoxifen 20mg)

Cytotam 20mg (Tamoxifen 20mg) is a type of nonsteroidal agent which interlinked to estrogen receptors (ER), provoke a conformational change in the receptor. This results in a inhibits in the verbalization of estrogen based on genes.
Combine of Cytotam 20mg (Tamoxifen 20mg) is extended to the nuclear chromatin of these consequence will reduced DNA polymerase action, repair thymidine discharge and restriction uptake of estradiol, hence lowers estrogen response.
Cytotam 20mg (Tamoxifen 20mg) enough that to concomitant with other co activators or co repressors in the tissue and fuse with different estrogen receptors,

Absorption of  Cytotam 20mg (Tamoxifen 20mg)

The time to high plasma concentration is 40mg/ml and Tmax is 5 hours after dosing.

Distribution of  Cytotam 20mg (Tamoxifen 20mg)

not available

Metabolism of  Cytotam 20mg (Tamoxifen 20mg)

In hepatic Cytotam 20mg (Tamoxifen 20mg) is metabolized.

Excretion of  Cytotam 20mg (Tamoxifen 20mg)

Route of excretion is 30% via fecal and 65% was excreted from the body
Half-life is 5 to 7 days

 SIDE EFFECTS  of  Cytotam 20mg (Tamoxifen 20mg)

COMMON SIDE EFFECT:
• High tumor pain
• Tumor site forming reddening
• Hair thinning
• Weight loss
• Stomach pains
• Sexual ability lost
• Hot flashes
• Vertigo . Serious side effects may be as follows, immediately inform the doctor:
• Thirst
• muscle weakness
• restlessness
• loss of appetite
• Vision difficulty
• Fever
• Blisters
• Abscess on the, throat, face, lips, eyes, tongue, ankles or lower legs.

PRECAUTIONS  of  Cytotam 20mg (Tamoxifen 20mg)

Consult with the doctor or pharmacist as if you have allergic condition against Cytotam Cytotam 20mg (Tamoxifen 20mg) or any of the compound in Tamoxifen tablets.
• Consult with the doctor that you have or have ever had renal, hepatic, or cardiac problem
• Consult with the doctor that are you pregnant or plan to become pregnant. Do not have plan for children while on treatment with Cytotam 20mg (Tamoxifen 20mg). You must use a specific method of conceiving to prevent pregnancy in yourself or your partner during your treatment with Cytotam 20mg (Tamoxifen 20mg) the drug will harm the fetus.
• Avoid breast feeding while on treatment with Cytotam 20mg (Tamoxifen 20mg)
• Use drug with caution due to early breast cancer signs hence during treatment with tamoxifen aware about development of breast cancer.
• Some important precautions should take care
• Effects in Metastatic breast cancer Patients
• Some breast cancer patients may report from hypercalcemia by starting few weeks treatment, if the condition occur and became severe then tamoxifen should discontinue.
• Effects on the Uterus-Endometrial Cancer and Uterine Sarcoma
• An incidence may increase with uterine malignancies and endometrial carcinoma is resulted with tamoxifen treatment.
• Non-malignant Effects on the uterus
• Due to estrogen properties of tamoxifen, an increased incidence of endometrial changes occurs involves like hyperplasia and polyps has been resulted. Hence the drug causes menstrual irregularity or amenorrhea.

DRUG INTERACTION of  Cytotam 20mg (Tamoxifen 20mg)

While interaction of Cytotam 20mg (Tamoxifen 20mg)with coumarin type anticoagulants combination will leads to increase in anticoagulant effects may occur.
Concomitant use of Bromocriptine with Cytotam 20mg (Tamoxifen 20mg)will increase the serum level of Cytotam 20mg (Tamoxifen 20mg) and N-desmethyl tamoxifen.

OVERDOSAGE of Cytotam 20mg (Tamoxifen 20mg)

Acute overdose is not considered in humans, in animals If administer heavy dose then leads in respiratory difficulties and convulsions and in human unsteady gait, acute neurotoxicity manifested by tremor, hyperreflexia, and vertigo was reported. There is no essential treatment for overdose. Thereby provide the patients by symptomatic supportive measures

 

CONTRAINDICATION of Cytotam 20mg (Tamoxifen 20mg)

Cytotam 20mg (Tamoxifen 20mg)is contraindicated in patients with as follows:
• Known hypersensitivity to the drug or its any ingredients
• Women concomitant use with coumarin- type anticoagulant treatment
• In women with deep vein thrombosis or pulmonary embolus history.

PREGNANCY  & LACTATION  of Cytotam 20mg (Tamoxifen 20mg)

Category D: Cytotam 20mg (Tamoxifen 20mg) while recommended to pregnant women will cause harm to fetal. Women are advised to stop the drug within 2 months and not become pregnant while taking Cytotam 20mg (Tamoxifen 20mg). And If sexually active then should use non-hormonal contraceptive measures.

DOSAGE of  Cytotam 20mg (Tamoxifen 20mg)

Regular adult dose for :
20 to 40mg for 5 years daily administer orally for breast cancer doses is > 20mg given by dividing dose (morning and evening) 20mg 5 years daily given orally for DCIS followed by surgery and radiation on breast
For 5 years administer 20mg daily taken orally to decrease the action of breast cancer in women at increased risk for breast cancer 20mg OD orally or 10mg twice daily orally given for adult dose for adjuvant breast cancer and Duration: 5 years
Pediatric dose for :
girls 2 to 10 years :
20mg once daily via oral route; duration up to 12 months administrated for McCune- Albright syndrome
20mg once daily via oral route; duration up to 12 months given for Precocious Puberty


STORAGE  of  Cytotam 20mg (Tamoxifen 20mg)

Keep away from children
Do not freeze
Keep the drug in a closed container at room temperature.


MISSED DOSE of  Cytotam 20mg (Tamoxifen 20mg)

Have the missed dose immediately before next dose duration
Next dose time arrived then left off the missed dose and follows regular schedule.
Avoid taking extra dose at same time.
Please consult the doctor for further details.

Brand name:
Cytotam
International trade name:
Soltamox
Active substance:
Tamoxifen
Strength:
20mg
Category:
Anti Cancer
Manufacturer:
Cipla Ltd
Packaging:
10 tablets
Product form:
Tablet

No reviews found

Write feedback
Worldwide delivery

Our company ships from India to all countries of the world.

Genuine and Authentic products

All products supplied from the manufacturer of WHO : GMP certified facilities and ISO Certified facilitates

Economical and Affordable prices

All the products are supplying from manufacturing companies of India