This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

Brand name:Lexiva

Active Ingeridents:Fosamprenavir Calcium

Company Name:Glaxosmithkline

Package:60 Tablets

Strength :700mg

Mechanism of action:

Lexiva (FOSAMPRENAVIR CALCIUM) is a prodrug that is rapidly hydrolyzed to amprenavir by cellular phosphatases in the gut epithelium as it is absorbed. Amprenavir is an inhibitor of HIV-1 protease. During HIV replication, HIV protease cleaves viral polypeptide products of the Gag and Gag-Pol genes to form structural proteins of the virion core and essential viral enzymes. Amprenavir interferes with this process by binding to the active site of HIV-1 protease, thereby preventing the processing of viral Gag and Gag-Pol polyprotein precursors, resulting in the formation of immature non-infectious viral particles.

Dosage and Administration:

Use Lexiva (FOSAMPRENAVIR CALCIUM) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Lexiva (FOSAMPRENAVIR CALCIUM). Talk to your pharmacist if you have questions about this information.

  • Take Lexiva (FOSAMPRENAVIR CALCIUM) by mouth with or without food.

  • Do not change your dose or stop taking Lexiva (FOSAMPRENAVIR CALCIUM) without talking with your doctor first. Continue to take Lexiva (FOSAMPRENAVIR CALCIUM) even if you feel well. Do not miss any doses.

  • Ask your health care provider any questions you may have about how to use Lexiva (FOSAMPRENAVIR CALCIUM).

Side effects:

Diarrhea, nausea, vomiting, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


Before taking Lexiva (FOSAMPRENAVIR CALCIUM), tell your doctor or pharmacist if you are allergic to it or to amprenavir; or if you have any other allergies. This product may contain inactive ingredients (such as propylene glycol in the suspension), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.


Store Lexiva (FOSAMPRENAVIR CALCIUM) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Do not use it after the expiration date. Keep Lexiva (FOSAMPRENAVIR CALCIUM) out of the reach of children and away from pets.


Lexiva (FOSAMPRENAVIR CALCIUM) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.