Trade name : Myezom
Active component : Bortezomib
Strength of the component : 2mg vial
Manufactured by : DR.Reddy's
Pack : 2mg Bortezomib containing vial in a carton
Dosage form : lyophilized powder
Category : Anti-cancer drug; proteasome inhibitor


Bortezomib is a drug sold under the brand name of Myezom 2mg which belongs to anti-neoplastic medicine, the main ingredient which is used as bortenat, which is available in the form of lyophilized powder Myezom 2mg is a prime benign proteasome inhibitor; proteasome is a biological structure that clefts the proteins Pharmacological grouped as: anti-neoplastic agent or proteasome inhibitor The drug is an prescription drug given under the supervision of pharmacist


The Myezom 2mg peak plasma level occurs as 509ng/ml
The Myezom 2mg has nearly 83% of human plasma protein binding.
Primarily metabolic pathway of Myezom 2mg is occurs by deboronation to form 2-deboronated metabolites which are inactive as 26S proteasome inhibitors. In liver Myezom 2mg is metabolized with the help of cytochrome P 450 enzymes 3A4, 2C19, & 1A2 by oxidation
The half life period of Myezom 2mg occurs at 9 to 15 hours In single dose IV;

In adults:
Multiple myeloma :
Previously untreated multiple myeloma In the therapy: Myezom dose 1.3mg/m2 should be given as 3 to 5 seconds via IV bolus or subcutaneous by interacting with tablet melphalan and prednisolone for nine 6 weeks treatment cycles Myezom is taken for two times weekly, (day 1, 4, 8, 11, 22, 25, 29 and 32) for Cycles 1 over 4 Myezom is taken once a week (day 1, 8, 22, and 29) for Cycles 5 over 9 Duration of Myezom is 72 hours
In Relapse stage :
The usual dose of Myezom is 1.3mg/m2 should be given via IV bolus or subcutaneous as two times for two weeks (day1, 4, 8, and 11) followed by a ten day rest course (day 12 through 21) Schedule of Treatment increased above 8 cycles may be taken once weekly for 4 weeks (day 1, 8, 15, and 22), followed by 13 day rest (day 23 over 35)
Important points :
Myezom administrated alone or combination with dexamethasone therapy cycle require of Three week course


The drug Myezom is a type of chymotrypsin like activity which is in form of unstable prohibitor of the 26S proteasome in human cells. The 26S proteasome is a group of protein that reduces the agglutinated proteins The various proteins are weakens by proteasome enzymes that make difficult to tumor cells persistence like cyclins, tumor suppressors, BCL-2 & cyclin dependent kinase inhibitors The functioning site of proteasome has Postglutamyl peptide hydrolysis activity Chymotrypsin like Trypsin like Prevention of these degenerations, sensitizes cells to apoptosis and cell arrest and leads to cell lysis


The usual dose of Myezom for untreated mantle cell lymphoma is; Myezom 1.3mg/m2 given as IV bolus given as two times weekly by concomitant with rituximab, cyclophospahmide, doxorubicin and tablet prednisolone for 2 weeks (day I, IV, VIII & XI) followed by rest period of 10 day (day II through 21). In Relapse stage: The regular dose of Myezom is 1.3mg/m2 administered as IV bolus or subcutaneous 2 times for two weeks (day I, IV, VIII & XI) followed by 10 day rest period (day II through 21) The treatment followed for above 8 cycles may be taken for once weekly for 4 weeks (day 1, 8, 15 & 22), followed by rest of 13 day (days 23 through 35) Lyophilized powder form is Myezom ; which is reconstituted by using 0.9% normal saline (NS) NaCl. Reconstituted the Myezom 2mg in 2ml of 0.9% NS The route of administration is IV bolus Intrathecal not use for administration


While taking Myezom 2mg some adverse effects occurs care should be taken in the conditions like Cardiac toxicity Pulmonary toxicity like Acute Respiratory Distress Syndrome, pneumonitis, interstitial pneumonia, lung infiltration. Posterior reversible encephalopathy syndrome-stop the Myezom 2mg therapy Myezom 2mg leads to peripheral neuropathy like burning sensation, hyperesthesia, hypoesthesia, paresthesia, neuropathic pain Manage postural Hypotension by altering the antihypertensive agents, hydration, and administration of mineralocorticoids or sympathomimetics Gastrointestinal toxicity-fluid or electrolyte replacements have to take Thrombocytopenia and neutropenia Tumor lysis syndrome Hepatic toxicity Embryo fetal toxicity.


Avoid interaction with st. Johns wort to decrease the exposure of Myezom 2mg while concomitant with CYP3A4 inhibitors: there is a chance of getting Myezom 2mg toxicity; so to reduce the dose of Myezom 2mg Interaction with Strong CYP3A4 inducers: decrease the exposure of Myezom 2mg while concomitant with melphalan-prednisone or dexamethasone alone No clinical effect on Myezom 2mg exposure.


Myezom 2mg is administer through IV bolus or subcutaneous; whereas intrathecal administration is contraindicated to the patients who are receiving Bortezomib Hypersensitivity reaction occurs in patients who are contraindicated to Myezom 2mg, boron, boric acid or glycine


Myezom 2mg is not a normal medicine used as anti-cancer drug; it is not to be self-medicated If a dose failed to take should consult with medical oncologist and followed the dosing schedules Avoid self administered Follow the advice given by physician and do not missed the cycles for course of therapy


Most common side effects occurred after administration of Myezom 2mg includes; Burning, crawling, itching, numbness, prickling ; Chest pain ; Black tarry stools; Bleeding gums ; Blood in urine ; Blurred vision ; Body aches, dizziness, faintness, nerve pain, painful urination, pale skin, runny nose, sore throat, stuffy nose, swollen glands, sunken eyes, ulcer, dry mouth, Cough producing mucus, ear congestion, loss of voice

Less common side effects

Belching, bone pain, difficulty with moving & bowel movements, cold and shivering, loss of appetite, loss of taste, muscle cramps, muscle pain, stomach discomfort. Vomiting, loss of weight discomfort, increased sensitivity of pain & touch, irregular breathing, heart beats, swelling of peripheral organs, thickening of bronchial secretions

We'd Like to Hear From You!


1., a fully licensed and regulated pharmacy, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.
2. will not dispense any prescription medication without a valid prescription from a licensed physician.
3. If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.
4. The drug information provided in the is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.
5. requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from
6. At, a Caregiver can order prescription medicines on your behalf.

This information should not be used to decide whether to accept this product or any other medicine. Only a health care provider is knowledge and training to decide that a medicine suitable for a specific patient. This information does not support any drug as safe, are effective or approved for the treatment of any patient or health condition. It's simple a brief overview of general information about this product. It does not include all information on possible applications, indications, warnings, precautions, interactions, adverse effects or risks that may be relevant to this product. This information is not specific medical advice and does not replace information obtained from your health care provider. You should check with your health care provider for complete information about the risks and benefits of using this product.