applepharmaceutical@gmail.com

Pomired - 2mg

drug

PRODUCT DETAILS

Brand name : Pomired
Active ingredient : Pomalidomide
Manufactured : Dr. Reddy’s
Strength : 2mg
Pack : 21 capsules in a container
Category : Anti-neoplastic drug

for MORE INFORMATION !!!

Pomired 2mg is a product which is endorsed by FDA, containing an active anti-cancer drug called Pomalidomide.
Pomired 2mg is available as orally bioavailable thalidomide derivative with various therapeutic activities such as;
Immuno modulatory
Anti-angiogenesis
Anti-neoplastic
Pomired 2mg is like thalidomide & Lenalidomide with related to decreased rate of serum aminotransferase elevations during treatment.
This may lead to severe liver injury.
Pomired 2mg is involved in the treatment for regression & unmanageable multiple myeloma.
Pomired 2mg is used in the patients who are failing to response for Lenalidomide treatment.
Pomired 2mg is used in combination with dexamethasone.

INDICATION

The major therapeutic indication of Pomired 2mg is involved in the treatment of multiple myeloma.
This treatment is occurred by combining with dexamethasone for reducing the side effect associated with Pomired 2mgomide.
Pomired 2mg is majorly indicated in patients who are not reacts for prior two therapies like Lenalidomide & proteasome inhibitor.

DOSAGE & ADMINISTRATION

The prescribed dose of Pomired in multiple myeloma is 4mg should be administered orally as once a day on day 1 to 21 of reciprocated 28-day cycles.
Pomired 2mg should be concomitant with dexamethasone.
Pomired 2mg capsules should be taken with or without food.
During hematological toxicities;
Neutropenia;
ANC (absolute neutrophils count) <500/mcl: Postpone the Pomired therapy and provide CBC weekly
ANC more than or equal to 500/mcl: Continue the Pomired3mg daily.
Thrombocytopenia:
Platelets count <25,000/mcL: postpone the Pomired treatment & follow the CBC
>50,000/mcL: continue 3mg of Pomired
Pomired 2mg with potent CYP1A2 inhibitor:
During this combination reduce the dose of Pomired by 50%
In renal impairment:
Initial dose of Pomired is 3mg
In hepatic impairment:
Mild to moderate condition, an initial dose of Pomired is 3mg; in severe condition, the initial dose of Pomired is 2mg.

WORK AS

Pomired 2mg exhibits various activities like :
Anti-neoplastic activity:
Prohibits proliferation
Promote apoptosis of hematopoietic cancer cells
Co adjuvant with dexamethasone in both Lenalidomide sensitive & resistant myeloma cells to activate the tumor cell apoptosis
Immuno modulatory:
Boosted the T-cells & natural killer cell mediate immunity.
The drug is prohibited the formation of pro-inflammatory cytokines by monocytes.
Anti-angiogenesis:
Interfere with formation of new vessels and leads to inhibit the cell division.

WARNING

There are two major worsening condition may occur during the treatment using with Pomired 2mg.
Embryo fetal damage :
Pomired 2mg capsules are contraindicated to pregnancy period.
During the treatment, patients avoid to becoming pregnant.
Use effective contraceptives for preventing pregnancy during therapy.
Venous & arterial thromboembolism :
Patient who are receiving Pomired 2mg capsules have chance of getting deep vein thrombosis, pulmonary embolism, myocardial infarction & stroke.
This type of condition should be treated by initiating prophylactic anti-thrombotic drugs.
The patients who are acquiring this condition then thromboprophylaxis should be provided

DRUG INTERACTION

Pomalidomide metabolism is mediated by CYP1A2 & CYP3A4.
The concomitant use of Pomired 2mg with CYP1A2 drugs like Fluvoxamine causes elevation of Cmax& AUC of Pomalidomide and concludes as increased concentration of Pomired leads to higher extent of adverse effects associated with Pomalid
In this condition, reduce the dose of Pomired 2mg and recommended.

CONTRAINDICATION

Pomired 2mg should be contraindicated to pregnancy & lactating women. The pregnancy category of Pomired 2mg is X.

SIDE EFFECTS

More common effects :
If taken during pregnancy, Severe life-threatening human birth defects
Fatigue
Weakness
Low white blood cell count
Anemia
Constipation
Nausea
Diarrhea
Shortness of breath
Upper respiratory infections
Back pain
Fever.
Less common effects :
Neuropathy
Dizziness
Confusion.

We'd Like to Hear From You!

PRESCRIPTION POLICY

1. myapplepharma.com, a fully licensed and regulated pharmacy, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.
2. myapplepharma.com will not dispense any prescription medication without a valid prescription from a licensed physician.
3. If you are ordering prescription medication(s), you hereby confirm that you will send us a scanned copy of your valid prescription(s) via email, fax, Whatsapp, or by post, and this prescription shall then be subject to the scrutiny of and approval by our qualified Pharmacists.
4. The drug information provided in the myapplepharma.com is for informative purposes only and this Website is not intended to provide diagnosis, treatment or medical advice. We are not liable for any adverse effects or harm to you as a result of your reliance on the information in the Website.
5. myapplepharma.com requires either the User or Customer or the Caregiver to confirm he/she is completely aware of the indications, side effects, drug interactions, effects of missed dose or overdose of the medicines he/she orders from us. It is imperative to seek professional advice from your physician before purchasing or consuming any medicine from myapplepharma.com.
6. At myapplepharma.com, a Caregiver can order prescription medicines on your behalf.


DISCLAIMER

This information should not be used to decide whether to accept this product or any other medicine. Only a health care provider is knowledge and training to decide that a medicine suitable for a specific patient. This information does not support any drug as safe, are effective or approved for the treatment of any patient or health condition. It's simple a brief overview of general information about this product. It does not include all information on possible applications, indications, warnings, precautions, interactions, adverse effects or risks that may be relevant to this product. This information is not specific medical advice and does not replace information obtained from your health care provider. You should check with your health care provider for complete information about the risks and benefits of using this product.