Caluran CP 50 Tablet

Description of Caluran CP 50 (Bicalutamide 50mg) tablet

Each tablet of Caluran CP 50 consists of bicalutamide 50mg, which is a pharmaceutical product that is used to treat prostate carcinoma among male patients. The drug is an androgen receptor antagonist that suppresses the growth of the endogenous on cancer cells.

Indications of Caluran CP 50 (Bicalutamide 50mg) tablet

Men who have metastatic castration-resistant prostate cancer are most often recommended the Caluran CP 50 (Bicalutamide 50mg) tablet. It can also be given to certain people with non-metastatic castration-resistant prostate cancer if their circumstances are kind of appropriate.

Mechanism of action of Caluran CP 50 (Bicalutamide 50mg) tablet

Bicalutamide assists by stopping signals from the androgen receptors, which reduces ability of androgens to assist growth of prostate cancer cells. This interruption leads to less spreading of cancer cells and more of cells dying.

How to consume Caluran CP 50 (Bicalutamide 50mg) tablet

People must use Bicalutamide tablet strictly in amount the doctor decides for you. Most often, drug is taken one time every day, and you can take it with food or without having any food. You have to make sure about swallowing each tablet whole and should not break, chew or open it.

Side Effects of Caluran CP 50 (Bicalutamide 50mg) tablet

1. Common side effects

• Feeling tired
• Experiencing hot flashes
• Problems with diarrhea
• Joint hurting
• Appetite gets lower

2. Serious side effects

• Having a seizures sometimes
• Indications of liver trouble (like having yellow skin or eyes)
• Allergic issues (rashes itchy, or swelling)

3. Rare side effects

• Heart-related cases (myocardial infarct for example)
• Bones can break
• Mood or action changes

Safety Advice for Caluran CP 50 (Bicalutamide 50mg) tablet

People who are using Bicalutamide need proper checking for probable bad impacts, for example, nerve symptoms including seizure. The doctor might ask for often checking of the liver working too.

Breastfeeding: Limited information is available regarding the use of this medicine in patients during breastfeeding. But on animal studies it shows a harmful effect on fetus, so it is better to avoid during breastfeeding.

Pregnancy: The use of this medicine is considered unsafe because this medicine may cause harmful effect on the fetus. Kindly consult with your doctor for further information.

Alcohol: There must be a reduction in taking alcohol since it might give higher risk of some impacts.

Liver: Patients having liver problems should use with care.

Lungs: If some lung disease is already there, it must be talked with your doctor before you start.

Kidney: Patients having kidney problems should use with care.

Driving: Tiredness and feeling dizzy can be possible, so machines and driving must be done with care.

Interaction of Caluran CP 50 (Bicalutamide 50mg) tablet

• Drug-Drug Interaction :

Flibanserin x Bicalutamide

It is contraindicated to use this medicine because the use of bicalutamide will increase the effect of flibanserin by affecting its hepatic enzyme metabolism.

Palifermin x Bicalutamide

Use alternative drug because the use of palifermin increases the toxicity of bicalutamide by other.

Ponesimod x Bicalutamide

Therapy should be administered with caution because the combination of this medicine increases the risk of infection.

Warfarin x Bicalutamide

Therapy should be administered with caution because the combination of this medicine may increase the concentration of vitamin k antagonists.

Taurine x Bicalutamide

The use of bicalutamide decreases the effect of taurine by unspecified interaction mechanism.

• Drug-Food Interaction:

Caffeine:

The use of caffeine containing products, including coffee, tea, and other energy drinks, should also be avoided when taking this medication as such as combination can result into insomnia, anxiety, and restlessness in predisposed people.

Alcohol:

The use of alcohol during this course of the therapy can cause confusion, drowsiness, and dizziness hence increasing the risk of accidents.

• Drug-Disease Interaction:

Liver Impairment:

Therapy should be administered with caution because this medicine metabolized in liver and the metabolism get altered in patients with moderate to severe liver impairment.

Contraindication of Caluran CP 50 (Bicalutamide 50mg) tablet

It is contraindicated to use this medicine in patient who have a history of allergy.

Do not take this medicine if you are pregnant.

The use of this medicine may decrease the glucose tolerance

Severe liver injury, breast pain, spermatogenesi inhibition, gynecomastia were reported.

Dosage of Caluran CP 50 (Bicalutamide 50mg) tablet  

The doctor may make changes depending upon personal tolerance and how the treatment is working.

Storage of Caluran CP 50 (Bicalutamide 50mg) tablets 

The storage of bicalutamide tablets must be carried out at average temperature of the room without being subjected to excessive moisture or heat. You should always have them inside packet they are in and out of reach of children.

Missed Dose to Caluran CP 50 (Bicalutamide 50mg) tablets

 If you miss one tablet, just use planned next dose on the regular schedule. Taking two tablets together to replace a missed one is not required. Do not try to increase your next dose for this.

Other General Information of Caluran CP 50 (Bicalutamide 50mg) tablets 

The use of Caluran CP 50 tablet might create dry skin, so using proper moisturizer is recommended by the doctors. Stay hydrated by drinking water and eat with more balanced as much as you can. Attending frequent checkups with doctor is important during treatment; you should notify any strange side effects as soon as possible. In case you need further advice or more information about your case, then visit your physician.

FAQs about  Caluran CP 50 (Bicalutamide 50mg) tablet

1. May Caluran CP 50 tablet cause infertility?

Currently there is scanty evidence that demonstrates the effect, preclinical studies indicate a possibility of an effect on reproductive paramaters.

2. Can Bicalutamide be used together with other pharmacologic agents?

Patients are expected to inform the physician treating them of all the co-existing medications, to alleviate the likelihood of drug-drug interaction.

3. What is necessary if an overdose happened?

Consultation with a doctor should be immediately sought in cause of an overdose.

4. Does the Caluran CP 50 tablet belong to the group of chemotherapeutic agents?

This drug is not a cytotoxic chemotherapy agent- it is an anti-androgen agent.

5. In case of perceived improvement should the treatment be stopped?

It is not recommended to suddenly stop using the medication before the prescribed dose of the therapy is achieved because early withdrawal can promote the growth of the remaining neoplastic cells.

Fact Box of Caluran CP 50 tablet

References