Instgra (Dolutegravir)

Dolutegravir
Contact us for more information
Цвет:
Вариант:
Wishlist Compare
Emcure Pharmaceuticals Ltd

Instgra (Dolutegravir)

ManufacturerEmcure Pharmaceuticals LtdBrand nameInstgraInternational trade nameTivicayActive substanceDolutegravirStrength50mgCategoryHIV

Description of Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) is additionally against retro viral medication, including Dolutegravir as a functioning part. Instgra 50mg (Dolutegravir 50mg) ought not to be utilized alone; it might consolidate with other hostile to retroviral operators for better action against HIV-1 diseases. Instgra 50mg (Dolutegravir 50mg) aren’t curing the HIV-1 disease, however used to control the quantity of HIV tallies in the body, and preclude HIV serious sick known as AIDS.

Medical use /Indication of Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) and are broadly demonstrated for the treatment of HIV-1 disease, in grown-ups and pediatric patients with body weight of 35kg incompletely. Instgra 50mg (Dolutegravir 50mg) are advantageous while mix; not in partitioned utilize

Mechanism of Action Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) contains contradicting to viral property against HIV make I sullying. Instgra 50mg (Dolutegravir 50mg) is stated as an Integrase inhibitor, which can counterpart to decrease HIV cell change by interceding with Integrase accomplish to the aggressive site and blockade of strands trade step happened. The viral DNA mix into have cells get stopped This trade procedure is accountable for HIV cell increment cycle. This prompts impediment of viral development

Absorption of Instgra 50mg (Dolutegravir 50mg)

Greatest plasma concentration time of Dolutegravir is 2 to 3 hours .The persistent state level reaches inside 5 days

Distribution of Instgra 50mg (Dolutegravir 50mg)

Dolutegravir is largely bound to human plasma protein at 98.9%

Metabolism of Instgra 50mg (Dolutegravir 50mg)

The metabolism of Dolutegravir is happens through UGT1A1 with some extra commitment from CYP3A.

Elimination of Instgra 50mg (Dolutegravir 50mg)

The terminal half existence of Dolutegravir is 14 hours. The significant course of disposal is urine and as an unaltered frame through feces.

Side effects of Instgra 50mg (Dolutegravir 50mg)

The adverse effects occur in this therapy; Liver toxicity Anaphylactic reactions Immune reconstitution syndrome

The most common side effects like; Insomnia Neutrophils elevation Increase in lipase Anxiety Depression Creatine kinase elevation

Drug interaction of Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) joins with drugs released through OCT2 or MATE1 (dofetilide or metformin), causes elongation of plasma concentration of these medicines. Instgra 50mg (Dolutegravir 50mg) joined with etravirine causes lessen in plasma dissemination of Dolutegravir. Instgra 50mg (Dolutegravir 50mg) at the same time used with threatening to mycobacterials, against convulsants or herbal product like st. Johns wort causes depletion in plasma dissemination of Dolutegravir. Dolutegravir is a substrate of UGT1A3, UGT1A9, BCRP and P-gp transporters. Instgra 50mg (Dolutegravir 50mg) joined with the prescription which prohibits these synthetic compounds or transporters cause, growing the plasma concentration of Dolutegravir. Instgra 50mg (Dolutegravir 50mg) tablets is specialist use with non-nucleoside reverse transcriptase inhibitors; causing utilization of effect of union of Instgra 50mg (Dolutegravir 50mg). If Instgra 50mg (Dolutegravir 50mg) tablets are solidifies with protease inhibitor causes decreasing in plasma appropriation of Dolutegravir.

Pregnancy of Instgra 50mg (Dolutegravir 50mg)

The pregnancy classification of Dolutegravir is B .Using Instgra 50mg (Dolutegravir 50mg) in pregnancy condition with caution, essentially in the wake of knowing the danger parts to the hatchling of these things.In Some patients placental change happens, in such conditions stop the utilization of these products.

Lactation of Instgra 50mg (Dolutegravir 50mg)

In body weight of the pediatric patients no less than 35kg, hostile to retro viral treatment is relevant. In the body weight of under 25kg: The strength of the Instgra 50mg (Dolutegravir 50mg) ought not to be evaluated.

Pediatric of Instgra 50mg (Dolutegravir 50mg)

In body weight of the pediatric patients no less than 35kg, hostile to retro viral treatment is relevant. In the body weight of under 25kg: The strength of the Instgra 50mg (Dolutegravir 50mg) ought not to be evaluated.

Dosage of Instgra 50mg (Dolutegravir 50mg)

Patients creatinine freedom, urine protein, urine glucose ought to be observed occasionally. Instgra 50mg (Dolutegravir 50mg): Comprising of 50mg of Dolutegravir

The dosage recommendation of Instgra 50mg (Dolutegravir 50mg)

The standard endorsed dosage of both the product is one tablet ought to be directed orally as a single dosage. Instgra 50mg (Dolutegravir 50mg) ought to be taken with or without meal. Instgra 50mg (Dolutegravir 50mg) ought to have the capacity to take in adults patients and pediatric having body weight of no less than 35kg.

Storage of Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) container should be kept at 25℃, protect the container away from light, moisture & heat.

Missed dose of Instgra 50mg (Dolutegravir 50mg)

Instgra 50mg (Dolutegravir 50mg) are unfriendly to retroviral prescription, if missed measurements occurred over the traverse of treatment, must be direct with therapeutic master and take after the rule as indicated by their suggestion. On the other way, the missed dose should be avoided and take the standard schedule.

Brand name:
Instgra
International trade name:
Tivicay
Active substance:
Dolutegravir
Strength:
50mg
Category:
HIV
Manufacturer:
Emcure Pharmaceuticals Ltd
Packaging:
30 Tablet
Product form:
Tablet

No reviews found

Write feedback
Worldwide delivery

Our company ships from India to all countries of the world.

Genuine and Authentic products

All products supplied from the manufacturer of WHO : GMP certified facilities and ISO Certified facilitates

Economical and Affordable prices

All the products are supplying from manufacturing companies of India