Brand Name : Spegra
Active components :Dolutegravir,Emtricitabine & TAF
Manufactured by : Emcure
Category : HIV
Package : 30 tablets


Spegra tablets Is a combination of dolutegravir,emcitarabine,temnofovir alafenamide . Spegra belongs to the calss of agent known as anti-retroviral agents. Spegra tablet is used to treat HIV type I infection. Spegra tablet preferred for HIV infection, it is non-curable and non-preventable. But the growth of HIV virus can be suppressed and leads to elevate immune cells .


Liver toxicity
Monitor the liver function test Maintain the hepatic enzymes In severe condition, stop the treatment
Bone defects
Loss of calcium levels occur causes osteomalacia while on treatment Prevent the problem by providing vitamin D supplements.
Fat redistribution
Discontinue the Spegra tablets
QT prolongation
QT prolongation reduced by avoiding the concomitant use of Spegra with drugs which may extends the QT intervals.


• Nausea
• Fatigue
• Abdominal pain
• Vomitting
• Anemieadeacresed platlet count
• Increased serum creatinin
• Diarrhea
• Upper respiratory tract infection


Spegra is contraindicated to patients who are concomitantly received elbasvir & grazoprevir. Hypersensitivity reactions of Spegra are produced due to patients is contraindicated to the component of Spegra.


Please consult the doctor. Maintain the regular dosing schedule Avoid the missed dose if possible Do not self medicate the Spegra tablets. Spegra is a three drug mixed dose regimen, caution should be taken during therapy using with Spegra tablets.

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