Generic : Abiraterone acetate
Trade name : Zelgor 250mg
Manufactured by : Sun pharmaceuticals.
Container : 120 tablets


Abiraterone acetate is sold under brand name Zelgor. Zelgor is belongs to type of anti-cancer medication that will act by decline the androgen production in the body. Androgen is a male hormone that canmaintained the tumor cell in prostate glands, the main ingredient which is used as abiraterone. Actually this drug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone.


The prescribed dose of Zelgor is initial as 4 tablets given orally once daily. The drug Zelgor administrated combination with 5mg prednisolone twice daily in empty stomach. Zelgor Tablets given on an empty stomach. Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zelgor Tablets is taken. Swallowed whole with water. Chew the tablets or Do not crush.


Androgens are balance the production of malignant in prostate. Zelgor is belongs to anti androgen drugs, that causes to suppress the enzyme17α-hydroxylase C 17, 20-lyase (CYP17), it is involves in androgen conglomerate. Reduce the serum testosterone level. Declined the tumor cell occurred.


Time to maximum plasma concentration of Zelgor tablet takes 12 hours.
Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein.
The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate.
The drug mainly excreted in 88% feces and 5% in urine Half-life of tablet Zelgor is 12 ± 5 hours.


Interaction of Zelgor with dextromethorphan will raises the Cmax and AUC of dextromethorphan Interaction Zelgor with strong CYP3A inhibitors or inducers , concomitant use with caution because pharmacokinetics is not evaluated.


Any allergy, serious liver problem or pregnant in patient, Zelgor therapy should be stopped Avoid taking of other medications, i.e prescription, over-the-counter, vitamins, herbal remedies, etc be sure to inform the doctors before the treatment. Do not take Aspirin administrated and products containing aspirin till doctor particularly allow the drug.


Zelgor has no essential antidote, If overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function.


If patient missed the dose of Zelgor, that missed dose will be skipped and follow the regular dosing schedule.


Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka level, Adrenocortical insufficiency Musculo skeletal and Connective tissue disorders:Joint swelling, discomfort, muscle discomfort General Disorder: Oedema Cardiac disorders: Hot flush, hypertension, arrhythmias, chest pain, cardiac failure GIT disorders: Diarrhea, dyspepsia Infections and Infestation:UTI Pulmonary disorder: Cough Renal:Urinary frequency, nocturia Injuries: Fractures


The drug stored at 15℃-30℃. Keep the drug in dry place.

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